Kinetic Chromogenic Method for Endotoxin Detection - China Suppliers & Factory Product for Research Use Only

The Kinetic Chromogenic Method is a highly sensitive and quantitative technique designed for the detection of bacterial endotoxins, specifically the lipopolysaccharides derived from Gram-negative bacterial cell walls. This method is essential for ensuring the safety of pharmaceuticals, medical devices, and biological products, as endotoxins can lead to serious pyrogenic reactions such as fever and shock in humans.

Our kinetic chromogenic endotoxin assay offers a reliable quantitative approach for identifying Gram-negative bacterial endotoxins. This assay employs a co-lyophilized lysate that combines Limulus Amebocyte Lysate (LAL) with a chromogenic substrate. Utilizing a kinetic microplate reader, the assay measures the rate of color change in the mixture of the lysate and the sample over time, recording absorbance changes at a wavelength of 405nm while maintaining a constant temperature of 37℃.

The reaction rate is directly related to endotoxin concentration: as endotoxin levels rise, the reaction accelerates, reducing the time required to achieve a predetermined absorbance threshold. It is important to note that this product is not registered with the U.S. FDA and is intended for research use only within the U.S. For clients seeking reliable sources, our factory in China provides high-quality endotoxin detection solutions, making us a preferred choice among suppliers.