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Endotoxin-Free Buffer Solutions for LAL Assays - Trusted China Suppliers & Factory for Accurate Testing

This reconstitution buffer is specifically designed for bacterial endotoxin tests, featuring **ultra-low endotoxin levels** (typically ≤0.005 EU/mL) that comply with USP/EP pharmacopoeia standards. This ensures the elimination of background interference, leading to highly accurate BET results. Our product exhibits excellent **compatibility** with widely used endotoxin-detecting methods, including LAL gel-clot, turbidimetric, and chromogenic assays, as well as with various test samples such as drugs, medical devices, and biologics, effectively preventing false positives and negatives, With a **stable pH range** (usually 6.0-8.0) and optimized ionic strength, this buffer maintains the activity of Limulus Amebocyte Lysate (LAL) reagent, thus guaranteeing consistent reaction conditions for endotoxin detection. The solution is **sterile-filtered** using a 0.22 µm membrane to eliminate microorganisms and particulates, and is formulated without endotoxin-contaminating components, such as certain surfactants, ensuring its purity, This product is ideal for pharmaceutical, medical device, and biotech labs, facilitating convenient sample reconstitution and dilution while streamlining test workflows. As a leading **China factory** and trusted **suppliers** of endotoxin detection solutions, we are committed to providing reliable products that meet the stringent needs of the industry

    Catalog Number

    Catalog No. Description Note Package
    TB20 50mM Tris buffer, pH7.0, 20ml/vial Used to dilute highly acidic or basic samples. 24 vials/pack
    TB50 50mM Tris buffer, pH7.0, 50ml/vial 12 vials/pack
    MB20 10mM Magnesium Buffer, 20ml/vial Used to overcome chelation effect. 24 vials/pack
    GB20 β-glucans blocker, 20ml/vial Used to block β-glucan interference in Limulus Amebocyte Lysate endotoxin reactions. 24 vials/pack

    Frequently Asked Questions

    What is the primary function of the 50mM Tris buffer (TB20/TB50)?
    The 50mM Tris buffer (pH 7.0) is specifically formulated to dilute highly acidic or basic samples, ensuring the pH level is adjusted to the optimal range required for the Limulus Amebocyte Lysate (LAL) endotoxin test.
    Why should I use the 10mM Magnesium Buffer (MB20)?
    The Magnesium Buffer (MB20) is utilized to overcome the chelation effect in samples that contain chelating agents, which can otherwise interfere with the LAL endotoxin reaction.
    How does the β-glucans blocker (GB20) improve assay specificity?
    GB20 blocks β-glucan interference in Limulus Amebocyte Lysate (LAL) reactions, preventing false-positive results and ensuring that the detection is specific only to endotoxins.
    What are the packaging options available for the Tris Buffer?
    The 50mM Tris Buffer is available in two sizes: TB20 (20ml/vial, packaged with 24 vials per pack) and TB50 (50ml/vial, packaged with 12 vials per pack).
    Are these buffers compatible with standard LAL endotoxin testing?
    Yes, these buffers and blockers are specifically designed and optimized to support and stabilize reactions in Limulus Amebocyte Lysate (LAL) endotoxin assays.